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Hijacking the Immune System: Cancer's Cunning STING Operation and a Revolutionary Tool in Battle Against Metastasis

Hijacking the Immune System: Cancer’s Cunning STING Operation and a Revolutionary Tool in Battle Against Metastasis

Researchers from the Memorial Sloan Kettering Cancer Center and Weill Cornell Medicine have discovered that a normally protective part of the immune system, the STING pathway, can inadvertently aid the spread of cancer. Using a computational tool named ContactTracing, they revealed that ongoing activation of this pathway can desensitize the immune system to cancerous growths. The study also identified chromosomal instability, where cell division is abnormal, as a major factor in cancer metastasis. The STING pathway aids the collaboration between such unstable cells and immune cells, thereby promoting cancer spread. This discovery, confirmed in both healthy cells and human tumor samples, offers insights into cancer progression and potential targets for therapy.

Full article here: https://ipllfirm.com/all-insights/news-and-articles/hijacking-the-immune-system-cancers-cunning-sting-operation-and-a-revolutionary-tool-in-battle-against-metastasis/